Bone Markers

• Vitamine D
• PTH (Parathyroid hormone)
• Calcium
• Phosphorus

When is it ordered?

Testing may be performed along with other tests such as a calcium, vitamin D, thyroid testing, and parathyroid hormone when bone loss is detected during a bone mineral density test (diagnostic imaging) and/or when a person has a history of unexpected bone fracture.
In children, testing may be done when they have signs and symptoms suggesting a metabolic bone disorder, such as:

• Bone and/or joint pain
• Increased frequency of fractures
• Delayed growth and bone development
• Deformed bones
• Brittle teeth

For managing and treating bone diseases, one or more bone marker tests may be performed prior to anti-resorptive or bone formation therapy and then typically 3 to 6 months later to monitor the effectiveness of treatment.